Uptake of mevalonate and acetate during plastid development.

نویسندگان

  • A R Wellburn
  • R Hampp
چکیده

1. The envelopes of etioplasts and 1-2h etiochloroplasts are permeable to mevalonate, but plastids from etiolated tissue illuminated for longer than 4h show progressive impermeability towards mevalonate. 2. Acetate permeates the envelopes of 1-4h etiochloroplasts but does not significantly cross the envelopes of etioplasts or 8-24h etiochloroplasts. 3. A translocator system exists within the plastid envelopes for mevalonate which relies on malate as a counter-exchange anion.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Envelope Permeability to Possible Precursors of Carotenoid Biosynthesis during Chloroplast-Chromoplast Transformation.

During the transformation of chloroplasts to chromoplasts in Capsicum annuum L., the permeability of the envelope membranes to possible precursors of carotenoid biosynthesis (acetate, mevalonate, citrate) was tested. The plastids were isolated by gel filtration, and the uptake of labeled compounds was measured by a filtering centrifugation technique, using silicone oil. The different ripening s...

متن کامل

Vitamin a and Isoprenoid Synthesis in the Rat.

1. Vitamin A-deficient rats were compared with similar animals given small amounts of vitamin A sufficient for adequate growth and with animals given large amounts of vitamin A. The effects of pair-feeding and feeding ad libitum were compared. 2. Ubiquinone and cholesterol concentrations in liver were measured at various stages of the deficiency, and the uptake of radioactive mevalonate and ace...

متن کامل

Isoprenoid Biosynthesis and Stability in Developing Green and Achlorophyllous Leaves of Rye (Secale cereale L.)

Formation o f major prenylquinones and carotenoids was investigated by comparing the incorporation o f [14C]mevalonate into segments o f different age from green and etiolated leaves o f 22 °C-grown rye seedlings (Secale cereale L.) and from 32 °C-grown rye leaves which contained bleached and proplastid-like ribosome-deficient plastids, due to a heat-sensitivity o f 70S ribosome formation. The ...

متن کامل

Extensive incorporation of (2-14C) mevalonic acid into cholesterol precursors by human platelets in vitro.

Human platelets convert [l-W]or [2J4C]acetate to labeled CO2 and fatty acids; the latter, in turn, become esterified to acylglycerols and phospholipids. However, acetate apparently does not reach mevalonate in the sterol pathway. By contrast, with [2J4C]mevalonate as substrate, there is labeling of farnesol, farnesoic acid, squalene, lanosterol, and dihydrolanosterol in the chloroform-soluble f...

متن کامل

I-28: Role of Mevalonate-Ras Homology (Rho)/Rho-Associated Coiled-Coil-Forming Protein Ki nase-Mediated Signaling Pathway in The Pathogenesis of Endometriosis-Associated Fibrosis

Background: Endometriosis, a disease affecting 3-10% of women of reproductive age, is characterized by the ectopic growth of endometrial glands and stroma surrounded by dense fibrous tissue. Whereas, normal eutopic endometrium shows scarless tissue repair during menstrual cycles, which suggests that the endometriotic tissues have distinct mechanisms of fibrogenesis. During the development of en...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Biochemical journal

دوره 158 2  شماره 

صفحات  -

تاریخ انتشار 1976